Ethan Hunt and the IMF team join August Walker, a CIA assassin, to avert an epic disaster. Weapon merchant John Lark and a group of terrorists known as the Apostles plan to use three plutonium nuclei for a simultaneous nuclear attack on the Vatican, Jerusalem and Mecca in Saudi Arabia. When the weapons disappear, Ethan and his crew find themselves in a desperate race against time to keep them from falling into the wrong hands.

Ethan Hunt and the IMF team join August Walker, a CIA assassin, to avert an epic disaster. Weapon merchant John Lark and a group of terrorists known as the Apostles plan to use three plutonium nuclei for a simultaneous nuclear attack on the Vatican, Jerusalem and Mecca in Saudi Arabia. When the weapons disappear, Ethan and his crew find themselves in a desperate race against time to keep them from falling into the wrong hands.